Top 14 HIPAA Software Developers in 2025

A vast array of software is required to run an efficient and successful healthcare organization, and all software developed for this purpose must be fully HIPAA-compliant and hosted on HIPAA-compliant infrastructure. Building software for the healthcare sector now requires a zero-trust approach to data security, strict adherence to federal regulations, and continuous risk validation across users, devices, and networks. In 2026, leading development firms are integrating secure LLMs, automated audit trails, and advanced identity controls directly into patient management systems to reduce PHI exposure. We have vetted these 14 firms based on their history of HIPAA compliance, technical execution, HITRUST readiness, and their ability to build secure, scalable medical applications.

The Health Insurance Portability and Accountability Act (HIPAA) sets the standard for protecting sensitive patient data. Companies that handle protected health information (PHI) must implement physical, network, and process security measures and follow them to ensure HIPAA Compliance.

HIPAA regulations apply to all healthcare websites and software applications, and developers must comply with the mandatory HIPAA requirements, paying particular attention to how PHI is accessed and which data must be fully encrypted. This includes implementing stringent access controls, audit trails, and data encryption for information both in transit and at rest. Following these rules ensures that all protected health information (PHI) is safely stored, transmitted, and accessed by an application, safeguarding patient privacy and protecting the organization from significant penalties.

Why Do You Need Help from a HIPAA-compliant Software Developer?

Because developers must adhere to strict regulations, developing HIPAA-compliant software is a complex and time-consuming process. Modern healthcare platforms must also implement zero-trust architecture, enforce least-privilege access, maintain detailed audit logs, and align with HITRUST readiness requirements to satisfy enterprise buyers and compliance officers. Choosing a leading software company to develop HIPAA-compliant solutions is essential to meet your healthcare organization’s growing technical needs. You should research your options carefully and be sure to work with a software development company that has extensive experience in building HIPAA-compliant software solutions — including secure cloud deployments, HIPAA Business Associate Agreement (BAA) signing policies, encrypted data pipelines, and EHR integrations, such as Epic or Cerner, where required.

To help you choose a trusted and experienced partner, we have collated a list of the top 14 HIPAA-compliant software developers. These are development houses that meet and exceed HIPAA’s physical, technical, and administrative safeguards. Our evaluation also factors in each company’s approach to zero-trust security models, experience with HITRUST-aligned environments, ability to support automated compliance reporting, and transparency around BAA execution. In compiling our list, we have considered each company’s experience in providing solutions to healthcare providers, reviews from previous clients, and its market presence.

Leading HIPAA-Compliant Software Developers

The companies below have proven experience building HIPAA-compliant applications with strong security controls and scalable architecture. We evaluated them based on zero-trust implementation, HITRUST readiness, BAA signing practices, and EHR integration capabilities, including Epic and Cerner.

1. Arkenea

Arkenea, ranked among the top preferred healthcare software development companies, provides healthcare organizations with reliable, scalable, HIPAA-compliant mobile and web applications. Arkenea is the only software development company that is fully dedicated to the healthcare industry. With more than 9 years of healthcare-focused delivery, Arkenea builds platforms aligned with HIPAA safeguards, HITRUST readiness requirements, and zero-trust security principles to protect PHI across cloud environments.

• Exclusive Healthcare Focus: Arkenea dedicates its entire practice to the healthcare sector, ensuring deep domain expertise in building solutions like patient portals, EHR/EMR systems, and practice management software.
• Regulatory Compliance & Zero-Trust Architecture: The team embeds HIPAA controls, HITRUST-aligned frameworks, least-privilege access, encryption at rest and in transit, and automated audit logging directly into the software development lifecycle from the initial design phase.
• Custom Web & Mobile Applications with EHR Integration: They specialize in creating bespoke, user-friendly applications for both web and mobile platforms, with experience integrating securely with major EHR systems where required, designed to improve clinical workflows and enhance patient engagement securely.

2. Mobisoft Infotech

Mobisoft Infotech is a leading software development company specializing in delivering HIPAA-compliant healthcare solutions to organizations worldwide. With over 13 years of experience in developing innovative mobile and web applications, Mobisoft Infotech offers end-to-end services from custom software development to integration, testing, and maintenance. The company incorporates zero-trust security architecture, identity-based access controls, encrypted data storage, and automated audit trails to safeguard PHI across modern cloud environments. Mobisoft Infotech is committed to creating secure, scalable, and compliant solutions that meet healthcare regulatory standards and align with HITRUST security frameworks. Trusted by healthcare providers and digital health companies, Mobisoft Infotech empowers organizations with solutions that improve patient care and operational efficiency.

• End-to-End Development Services: Mobisoft Infotech manages the entire product lifecycle, from initial consultation and strategic planning through to development, deployment, and ongoing maintenance and support, embedding security and compliance validation into each phase.
• Innovative Digital Health Solutions: The company builds applications for telemedicine, remote patient monitoring, and digital therapeutics with strong encryption standards and structured access controls to minimize PHI exposure.
• Custom Web & Mobile Applications with EHR Integration: They deliver secure web and mobile healthcare platforms and have experience integrating applications with major EHR systems such as Epic and Cerner when client infrastructure requires interoperability.
• Global Delivery Model: With a worldwide presence, they offer flexible engagement models and a structured delivery framework to support healthcare startups, providers, and enterprise organizations.

3. Technology Rivers

Technology Rivers is a Virginia-based custom software development firm that specializes in HIPAA-compliant web and mobile app development. Technology Rivers works with healthcare entrepreneurs, startups, and health-tech organizations to create secure and scalable healthcare solutions. The company incorporates zero-trust security architecture, encrypted data flows, and detailed audit logging into its development lifecycle to reduce PHI exposure risks. Their work includes native and cross-platform hybrid mobile apps, web applications, desktop applications, and integrations with EMR & EHR systems such as Epic and Cerner.

• EMR & EHR Integration Specialists: The company excels at creating smooth integrations with major electronic health record systems, such as Epic and Cerner, ensuring that new applications operate securely within existing clinical IT ecosystems.
• Startup and Innovator Focused: Technology Rivers partners with health-tech entrepreneurs and startups, providing the technical expertise needed to transform concepts into compliant, production-ready healthcare software platforms.
• Cross-Platform Development with Secure Architecture: They develop both native and hybrid mobile applications while implementing role-based access controls, encryption at rest and in transit, and structured monitoring to maintain HIPAA-aligned security standards.

4. Novelty Technologies

Novelty Technologies provides end-to-end software solutions for a wide range of clients, including healthcare organizations. Novelty Technologies caters to the entire development lifecycle, from web and mobile app creation and UI/UX design to data analytics and API integration. The company applies zero-trust security principles, encrypted data management, and structured access controls to protect PHI across cloud-based environments. Novelty has extensive experience working with HIPAA-compliant hosting partners, and security is embedded into its architecture and deployment strategy.

• Full-Lifecycle Project Management: Novelty Technologies oversees every stage of development, from initial concept and UI/UX design to backend engineering, API integration, and analytics implementation, ensuring compliance considerations are addressed throughout.
• Security-First & Zero-Trust Architecture: Security is a core component of their development approach, with role-based access, encryption at rest and in transit, and audit logging integrated into applications to meet HIPAA safeguards.
• EHR & Secure Infrastructure Experience: The team has experience integrating healthcare applications with major EHR systems, such as Epic and Cerner, as required, and collaborating with HIPAA-compliant hosting providers to deploy secure, resilient solutions.

5. ZDI

ZDI is a leading digital marketing company and a proud partner of Atlantic.Net. ZDI has strong ties with HIPAA-compliant organizations and provides several services to healthcare clients, including website and mobile app design, brand creation, and content creation. The company incorporates zero-trust security principles, encrypted data transmission, and structured access controls when developing healthcare websites and applications that may handle protected health information (PHI). ZDI won the GDUSA Health + Wellness Design award in 2017 and has created some excellent web applications for our clients.

• Healthcare Marketing and Design: ZDI combines technical development with a strong focus on digital marketing, helping healthcare organizations create a powerful brand presence through compelling web design and content strategy, while maintaining HIPAA-aligned security safeguards.
• Award-Winning Design Acumen: As a winner of the GDUSA Health + Wellness Design award, ZDI demonstrates a proven ability to create visually appealing and highly functional web and mobile applications for the health sector.
• Secure Integration Capabilities: ZDI can support integration with major EHR systems such as Epic and Cerner when interoperability with clinical platforms is required.
• complete Service Offering: Their services extend beyond simple development to include brand creation, patient-facing content development, and strategic marketing, providing a holistic solution for healthcare clients.

6. Let’s Talk Interactive

Let’s Talk Interactive has been doing amazing things for our friends in healthcare before, during, and after the COVID-19 pandemic. Telemedicine has become the first choice for frontline healthcare workers, and Let’s Talk provides HIPAA-compliant teleconferencing services, along with industry-leading virtual and walk-in clinic software, empowering healthcare professionals to conduct vital assessments of patients remotely over the phone or via video chat. Their platforms are designed with zero-trust security architecture, encrypted video sessions, identity-based access controls, and structured audit logging to protect PHI across virtual care environments.

• Telemedicine and Virtual Care Platforms: They are a leader in providing complete, HIPAA-compliant telehealth solutions, including secure video conferencing and software for managing virtual clinics and patient appointments, built with encrypted data transmission and role-based access controls.
• Remote Patient Assessment Tools with EHR Integration: Their software empowers clinicians to conduct vital remote assessments and integrates with major EHR systems such as Epic and Cerner, where interoperability is required.
• Proven Pandemic Response: The company has a proven track record of supporting healthcare providers with reliable, scalable virtual care technology, demonstrating its value during peak demand periods.

7. MobiDev

MobiDev is a custom software development company awarded as Best Upwork Software Development Agency 2016-2019. With more than 10 years of complete experience, MobiDev provides HIPAA-compliant mobile and web solutions integrated with the latest innovative technologies: Artificial Intelligence, Machine Learning, the Internet of Things, and Augmented Reality. The company implements a zero-trust security architecture, encrypted data processing, and detailed audit trails to protect PHI across AI-driven and connected health platforms.

• Advanced Technology Integration with Secure Architecture: MobiDev embeds AI for diagnostics, IoT for remote monitoring, and AR for clinical applications while implementing role-based access controls and encryption safeguards aligned with HIPAA requirements.
• Recognized Development Excellence: With multiple awards for their quality and client satisfaction, MobiDev has established itself as a trusted partner for complex custom software projects in the healthcare domain.
• EHR Integration Experience: MobiDev has experience integrating healthcare solutions with major EHR systems, including Epic and Cerner, where interoperability is required.
• Cross-Domain Expertise: Their decade of experience spans multiple industries, allowing them to bring fresh perspectives and innovative approaches to solving unique challenges within healthcare technology.

8. VAIRIX Software Development

VAIRIX Software Development is a nearshore software development company with extensive experience building HIPAA-compliant health and wellness apps. From virtual consultations and e-prescriptions to mental health counseling and support group features, their team of experts crafts products that help your users seamlessly manage their medical needs. Based out of Montevideo, Uruguay (UTC-3), VAIRIX provides staff augmentation and end-to-end development services to clients across the United States. Their development process incorporates zero-trust access controls, encrypted communications, and structured monitoring to reduce PHI exposure risks in cloud-based healthcare systems.

• Nearshore Development Model: Based in a US-friendly time zone, VAIRIX offers real-time collaboration and cost-effective development services, making them an ideal partner for American healthcare companies.
• Health and Wellness App Specialization: The team has deep expertise in creating consumer-facing applications for managing medical needs, including virtual consultations, e-prescribing, and mental health support platforms.
• EHR Integration Capabilities: VAIRIX can support integration with major EHR systems such as Epic and Cerner, where required to ensure interoperability with clinical environments.
• Flexible Engagement Options: VAIRIX provides both full end-to-end project development and staff augmentation, allowing clients to either outsource an entire project or supplement their in-house team with skilled developers.

9. Inoxoft

Inoxoft is a certified custom healthcare software development company. It offers custom healthcare solutions done by highly skilled professionals with extensive domain expertise. They’ve delivered top-notch medical software for a range of medical service institutions. Their clients include hospitals and healthcare startups, to whom they offer custom medical software development services. They’ll empower you with new ideas for leveraging medical care. Building custom healthcare solutions, Inoxoft engineers work with up-to-date technologies such as Python, .Net, Node.js, ReactJS, Flutter, and React Native. The company applies zero-trust security principles, encryption in transit and at rest, and structured audit logging to support HIPAA-aligned healthcare deployments.

• Certified Domain Expertise: As a certified healthcare development company, Inoxoft brings a high level of professionalism and domain-specific knowledge to projects for both established hospitals and innovative startups.
• Modern Technology Stack: Their engineers are proficient in a wide range of modern technologies, including Python, .Net, and React, enabling them to build high-performance, scalable, and secure healthcare applications.
• EHR Integration Experience: Inoxoft has experience integrating healthcare platforms with major EHR systems such as Epic and Cerner when required by hospital or provider workflows.
• Client-Centric Innovation: Inoxoft prides itself on empowering clients with new ideas and strategies for leveraging technology to improve patient care, streamline operations, and drive better clinical outcomes.

10. Belitsoft

Belitsoft has delivered technology solutions and services to the healthcare industry since 2015. The company focuses on long-term partnerships with its clients from the United States, the UK, Europe, and Israel. Belitsoft’s clients include healthcare startups, medical ISVs, hospitals, healthcare centers, private medical practices, pharmacy organizations, and medical and research laboratories. Belitsoft engages with third-party security auditors, such as OWASP and TrueSec, to guarantee safety and compliance with health IT standards and regulations. The company incorporates zero-trust security architecture, encrypted data handling, and structured audit logging into healthcare applications to support HIPAA-aligned deployments.

• Third-Party Security Validation: Belitsoft reinforces its commitment to security by engaging reputable third-party auditors such as OWASP and TrueSec, while embedding role-based access controls and encryption safeguards into its development workflows.
• Long-Term Partnership Focus: The company culture is built around forming durable, long-term relationships with clients, ensuring continuous support and the evolution of its software solutions.
• EHR Integration Experience: Belitsoft has experience integrating healthcare applications with major EHR systems, including Epic and Cerner, where interoperability is required.
• Broad Healthcare Clientele: They serve a diverse spectrum of the healthcare ecosystem, including hospitals, private practices, research labs, and pharmacies, giving them a holistic understanding of the industry’s needs.

11. TatvaSoft

TatvaSoft specializes in healthcare software development with over 18 years of experience developing custom software applications. They create HIPAA-compliant web, desktop, and mobile app solutions. They offer a broad spectrum of healthcare solutions, including EHR systems, telemedicine, and medical health applications for both patients and healthcare management professionals. TatvaSoft applies zero-trust access models, encryption at rest, and detailed monitoring controls to reduce PHI exposure across platforms.

• Multi-Platform Development with Secure Architecture: TatvaSoft has deep expertise in creating integrated solutions across web, desktop, and mobile platforms while implementing structured access controls and audit-ready systems.
• Wide Range of Healthcare Solutions: Their portfolio includes everything from complex Electronic Health Record (EHR) systems to user-friendly telemedicine platforms and practice management tools, underscoring their versatility.
• EHR Interoperability Capabilities: TatvaSoft can support integration with major EHR systems, such as Epic and Cerner, to enable secure data exchange for healthcare providers.
• Decades of Experience: With over 18 years in the custom software industry, TatvaSoft brings a wealth of experience and a mature development process to every healthcare project it undertakes.

12. ScienceSoft

ScienceSoft is an ISO 13485:2016, ISO 9001:2015, and ISO 27001:2013 certified IT consulting and software development company with 20+ years of healthcare IT experience, headquartered in McKinney, Texas, US, with offices in Europe and the Middle East. Experienced in HIPAA-compliant software development, ScienceSoft delivers software to leading healthcare organizations. The company incorporates zero-trust security principles, encrypted data governance models, and structured compliance monitoring into its healthcare IT solutions.

• Multiple ISO Certifications: ScienceSoft’s adherence to major ISO standards for quality management, medical devices, and information security demonstrates a formal commitment to the highest levels of quality and security.
• Deep Healthcare IT Consulting: With over 36 years of experience in artificial intelligence, the company delivers expert healthcare IT consulting and software development, applying advanced AI technologies to optimize clinical workflows, enhance patient care, and strengthen technology strategy.
• EHR Integration Expertise: ScienceSoft has experience integrating healthcare applications with major EHR systems, including Epic and Cerner, to ensure secure interoperability across clinical systems.
• Mature PMO Excellence: ScienceSoft’s dedicated PMO ensures predictable and compliant delivery of healthcare IT projects through proven governance, proactive risk management, and full transparency across scope, timelines, and budgets.

13. IT Craft

IT Craft is a leader within the software development industry, having recently been recognized as the “Top Web Developers, 2020” by Clutch, an independent research company based in Washington D.C. What sets IT Craft apart is its commitment to support clients through the completion of their project and beyond, providing all of its partners with high-quality post-launch support. This custom medical software provider delivers the development of new healthcare-related mobile and web applications, as well as the improvement and performance optimization of existing applications. IT Craft incorporates zero-trust security architecture, encrypted communications, and structured access management to support HIPAA-aligned healthcare deployments.

• Post-Launch Support Commitment: IT Craft distinguishes itself with a strong focus on long-term partnerships, providing complete post-launch support and maintenance to ensure applications remain secure and effective over time.
• Award-Winning Development Team: Recognition as a top developer by industry research firms such as Clutch validates their technical skills and ability to deliver high-quality web and mobile applications for their clients.
• EHR Integration Experience: IT Craft has experience integrating healthcare applications with major EHR systems, including Epic and Cerner, where interoperability with existing clinical infrastructure is required.
• New and Legacy System Expertise: They are skilled in building new healthcare applications from scratch and modernizing, improving, and optimizing legacy software systems for better performance.

14. LeewayHertz

LeewayHertz is a custom software development company that creates HIPAA-compliant healthcare apps for both startups and large healthcare organizations. They have built secure digital health platforms, patient engagement tools, and AI-powered healthcare apps. LeewayHertz uses zero-trust security, encrypted data storage, and structured audit controls to protect patient health information in cloud-based healthcare systems.

• Healthcare Software Development Expertise: LeewayHertz develops custom web and mobile healthcare solutions, including telehealth platforms, remote patient monitoring systems, and clinical workflow applications.
• Secure AI & Data Architecture: The company adds AI-driven features and uses role-based access controls, encryption for data in transit and at rest, and monitoring tools that meet HIPAA security standards.
• EHR Integration Experience: LeewayHertz has experience connecting healthcare platforms to major EHR systems, including Epic and Cerner, enabling interoperability with clinical environments.
• Enterprise & Startup Support: They work with both new health-tech startups and established healthcare providers, offering scalable software solutions that meet compliance requirements.

HIPAA-Compliant Developer Comparison (2026)

How Can Atlantic.Net Help?

The rapidly evolving field of healthcare technology can be a minefield for many healthcare professionals looking for compliant software solutions. With an ever-increasing workload, medical professionals are embracing new cloud-based platforms to improve the quality and speed of patient care. While technological advances can make life much easier for already stretched medical staff, ensuring the safety and security of confidential patient information can bring a new headache. Modern healthcare environments now require zero-trust network controls, encrypted storage, continuous monitoring, and detailed audit logging to properly safeguard PHI in the cloud.

As a healthcare provider, no matter which software solution you purchase, you must choose a fully HIPAA-compliant hosting platform that prioritizes security, privacy, and compliance to host the application. Atlantic.Net provides HIPAA-ready cloud infrastructure with encrypted data at rest and in transit, role-based access controls, secure backup options, and support for BAAs (BAAs). Atlantic.Net can offer you fully scalable, customizable cloud hosting solutions to meet your organization’s needs. Contact our sales team today to find out how Atlantic.Net can help your organization.